Fabrication of a novel hydrophobic/ion‐exchange mixed‐mode adsorbent for the dispersive solid‐phase extraction of chlorophenols from environmental water samples. Issue 16 (18th July 2016)

• Record Type: Journal Article
• Authors: Gao, Li; Wei, Yinmao
• Is Part Of: Journal of separation science. Volume 39:Issue 16(2016)
• Page Start: 3186
• Page End: 3194
• Publication Date: 2016-07-18
• Subjects: Chlorophenols -- Dispersive solid‐phase extraction -- High‐performance liquid chromatography -- Mixed‐mode adsorbent; Separation (Technology) -- Periodicals; Chromatographic analysis -- Periodicals; 543.089
• DOI: 10.1002/jssc.201501299
• Languages: English
• ISSNs: 1615-9306

Abstract

Abstract : A novel mixed‐mode adsorbent was prepared by functionalizing silica with tris(2‐aminoethyl)amine and 3‐phenoxybenzaldehyde as the main mixed‐mode scaffold due to the presence of the plentiful amino groups and benzene rings in their molecules. The adsorption mechanism was probed with acidic, natural and basic compounds, and the mixed hydrophobic and ion‐exchange interactions were found to be responsible for the adsorption of analytes. The suitability of dispersive solid‐phase extraction was demonstrated in the determination of chlorophenols in environmental water. Several parameters, including sample pH, desorption solvent, ionic strength, adsorbent dose, and extraction time were optimized. Under the optimal extraction conditions, the proposed dispersive solid‐phase extraction coupled with high‐performance liquid chromatography showed good linearity range and acceptable limits of detection (0.22∽0.54 ng/mL) for five chlorophenols. Notably, the higher extraction recoveries (88.7∽109.7%) for five chlorophenols were obtained with smaller adsorbent dose (10 mg) and shorter extraction time (15 min) compared with the reported methods. The proposed method might be potentially applied in the determination of trace chlorophenols in real water samples.