A 2-year-old Japanese girl with TNF receptor–associated periodic syndrome: A case report of the youngest diagnosed proband in Japan. Issue 5 (2nd September 2016)

• Record Type: Journal Article
• Authors: Yasumura, Junko; Wago, Masakuni; Okada, Satoshi; Nishikomori, Ryuta; Takei, Syuji; Kobayashi, Masao
• Is Part Of: Modern rheumatology. Volume 26:Issue 5(2016)
• Page Start: 798
• Page End: 801
• Publication Date: 2016-09-02
• Subjects: Autoinflammatory diseases -- Periodic fever -- Systemic juvenile idiopathic arthritis -- Tumor necrosis factor receptor-associated periodic syndrome; Rheumatology -- Periodicals; 616.723005
• DOI: 10.3109/14397595.2014.924894
• Languages: English
• ISSNs: 1439-7595

Abstract

Abstract : We report a 2-year-old girl with tumor necrosis factor receptor–associated periodic syndrome (TRAPS) who is the youngest proband diagnosed in Japan. Recurrent fever had started at her 6 months of age, and she had the familial history of recurrent fever, suggesting underlying genetic disorder, in her father and grandfather. Careful clinical observation of characteristics of fever with disease course and the familial history of recurrent fever may lead to diagnosis of TRAPS in early infancy.