Brønsted acid cocatalysis in photocatalytic intramolecular coupling of tertiary amines: efficient synthesis of 2-arylindols. Issue 31 (19th July 2016)

• Record Type: Journal Article
• Authors: Yuan, Xiaoqian; Wu, Xinxin; Dong, Shupeng; Wu, Guibing; Ye, Jinxing
• Is Part Of: Organic & biomolecular chemistry. Volume 14:Issue 31(2016)
• Page Start: 7447
• Page End: 7450
• Publication Date: 2016-07-19
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c6ob01239f
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : We report herein a highly efficient intramolecular coupling reaction of tertiary amines and ketones (α, β-unsaturated ketones) by using a Brønsted acid as a cocatalyst, affording 2-arylindols in good to excellent yields (up to 92%) under visible light irradiation at room temperature. Abstract : We report herein a highly efficient intramolecular coupling reaction of tertiary amines and ketones (α, β-unsaturated ketones) by using a Brønsted acid as a cocatalyst, affording 2-arylindols in good to excellent yields (up to 92%) under visible light irradiation at room temperature.