Early tooth loss in end‐stage renal disease patients on haemodialysis. (27th May 2016)

• Record Type: Journal Article
• Authors: Limeres, J; Garcez, JF; Marinho, JS; Loureiro, A; Diniz, M; Diz, P
• Is Part Of: Oral diseases. Volume 22:Number 6(2016)
• Page Start: 530
• Page End: 535
• Publication Date: 2016-05-27
• Subjects: tooth loss -- periodontal disease -- chronic kidney disease -- haemodialysis; Mouth -- Diseases -- Research -- Periodicals; 617.522
• DOI: 10.1111/odi.12486
• Languages: English
• ISSNs: 1354-523X

Abstract

Abstract : Objective: This article sets out to evaluate the prevalence and aetiopathogenesis of edentulism in patients on haemodialysis. Subjects and methods: The study group comprised 44 adult patients with end‐stage renal disease (ESRD) on haemodialysis. A control group was formed of 44 individuals matched for age and sex and with a glomerular filtration rate >90 ml min −1 . All participants underwent intra‐oral examination, gathering information on dental and periodontal status, and a saliva sample was taken to determine saliva debit and its biochemical composition. Results: The average number of missing teeth was higher in ESRD patients than in controls ( P = 0.018). Six (13.6%) fully edentulous individuals were detected in the study group and 1 (2.2%) in the control group. Some of the clinical and biochemical variables with statistically significant differences between the study group and the control group showed a significant relationship with the number of missing teeth, but the depth of the periodontal pockets presented the highest coefficient of determination (OR = 3511.1; 95%CI = 82.2–6834.3; P < 0.001; R 2 = 0.827). Conclusions: Premature tooth loss is common in haemodialysis patients. Although the aetiology and pathogenesis of this finding has still not been fully clarified, it appears that severe periodontal disease may play a relevant role.