A new phenolic compound with antioxidant activity from the branches and leaves of Pyrus pashia. Issue 10 (18th May 2016)

• Record Type: Journal Article
• Authors: Li, Zhen-Jie; Zheng, Xi; Wan, Chun-Ping; Cai, Le; Li, Ying; Huang, Lin; Ding, Zhong-Tao
• Is Part Of: Natural product research. Volume 30:Issue 10(2016)
• Page Start: 1136
• Page End: 1143
• Publication Date: 2016-05-18
• Subjects: Pyrus pashia -- phenolic constituents -- antioxidant activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1046130
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract : The branches and leaves of Pyrus pashia are used to cure abdominal pain and diarrhoea in Chinese folk medicine. A new phenilic compound, 4- O -β-d -glucopyranosylbenzyl-benzoate ester (1 ), along with 21 known ones (2–22 ) were isolated from the branches and leaves of this plant. Compounds2 and3 displayed remarkable antioxidant activities against 1, 1-diphenyl-2-picrylhydrazyl radical (IC50 = 13.26 ± 0.04 μM, 13.28 ± 0.11 μM, respectively), which were at the same grade as positive control rutin. The caffeoyl group in compounds2 and3 was supposed to play an important role in the antioxidant activities. Abstract :