Two new triterpenoid glycosides from the stems of Camellia oleifera Abel. Issue 13 (2nd July 2016)

• Record Type: Journal Article
• Authors: Yan, Qing-Wei; Fu, Hui-Zheng; Luo, Yue-Hua; Zhou, Guo-Ping; Wan, Kai-Hua; Zhong, Rui-Jian
• Is Part Of: Natural product research. Volume 30:Issue 13(2016)
• Page Start: 1484
• Page End: 1492
• Publication Date: 2016-07-02
• Subjects: Camellia oleifera Abel -- Theaceae -- triterpenoid glycosides; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1113529
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new oleanane-type triterpenoid glycosides, 3- O - β -D-xylopyranosyl-(1→2)- α -L-arabinopyranosyl-(1→3)-[ β -D-glucuronopyranosyl-(1→2)]- β -D-glucuronopyranosyl-22 α -angeloyloxyolean-12-ene-15 α, 16 α, 28-triol(1 ) and 3- O - β -D-xylopyranosyl-(1→2)- α -L-arabinopyranosyl-(1→3)-[ β -D-glucuronopyranosyl-(1→2)]- β -D-glucuronopyranosyl-21 β -acetyl-22 α -angeloyloxyolean-12-ene-16 α, 28-diol (2 ) were isolated from the stems of Camellia oleifera Abel. Their structures were elucidated by means of spectroscopic methods and chemical evidence. The cytotoxic activities of compounds1–2 were evaluated against five human tumour cell lines (HCT-8, BGC-823, A5049, and A2780). Compounds1–2 showed cytotoxic activity against five human cancer cell lines, with IC50 values ranging from 3.15 to 7.32 μM. Abstract :