New cytotoxic constituents from the Red Sea soft coral Nephthea sp. Issue 11 (2nd June 2016) - Hegazy, Mohamed-Elamir F.
Abstract : Nephthea are soft coral species rich in sesquiterpenoids and steroids. An organic extract of Nephthea sp. resulted in the isolation of a new steroid (1 ), as well as several previously reported metabolites (2 –9 ). Structures were elucidated by employing NMR and HR-EI-MS analyses. The total extract, fractions and purified compounds exhibited differential cytotoxicity against the breast cancer MCF-7 cell line. Abstract :