Two new benzolactones from the leaves of Nicotiana tabacum and their anti-tobacco mosaic virus activities. Issue 13 (2nd July 2016)

• Record Type: Journal Article
• Authors: Shen, Qinpeng; Xu, Xingmeng; Zhang, Fengmei; Xiang, Nengjun; He, Pei; Si, Xiaoxi; Zhu, Ruizhi; Wang, Kunmiao; Liu, Zhihua; Liu, Chunbo; Miao, Mingming
• Is Part Of: Natural product research. Volume 30:Issue 13(2016)
• Page Start: 1464
• Page End: 1469
• Publication Date: 2016-07-02
• Subjects: Nicotiana tabacum -- benzolactones -- anti-tobacco mosaic virus activities; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2015.1104675
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new benzolactones, 5-methyl-6-prenyl-isobenzofuran-1(3 H )-one (1 ), 5-hydroxymethyl-6-prenyl-isobenzofuran-1(3 H )-one (2 ), together with four known phenolic compounds (3–6 ), were isolated from the leaves of Nicotiana tabacum . Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds1–6 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compounds1–6 exhibited high anti-TMV activities with inhibition rates in the range of 16.9–26.2%, respectively. Abstract :