Pregnancy outcome after oocyte donation in patients with Turner's syndrome: Clinical experience and management. (18th May 2016)

• Record Type: Journal Article
• Authors: Deligeoroglou, Efthimios; Stergioti, Evgenia; Dimopoulos, Konstantinos D.; Karountzos, Vassileios; Prapas, Yannis
• Is Part Of: Journal of obstetrics and gynaecology. Volume 36:Number 4(2016)
• Page Start: 504
• Page End: 507
• Publication Date: 2016-05-18
• Subjects: Oocyte donation -- pregnancy -- Turner syndrome; Obstetrics -- Periodicals; Gynecology -- Periodicals; 618.05
• DOI: 10.3109/01443615.2015.1103714
• Languages: English
• ISSNs: 0144-3615

Abstract

Abstract : Turner's syndrome (TS) is a chromosomal defect with partial or total absence of the X chromosome. Our objective is to report our experience in Greece with patients suffering from TS and trying to conceive; therefore, we present four patients with TS, who underwent In vitro fertilization (ICSI) with donor oocytes in order to get pregnant. Three out of four patients managed to conceive and bring pregnancy to completion. It was shown that patients diagnosed in childhood or adolescence with TS have the possibility to undergo hormone replacement therapy (HRT) and thus, secondary sexual characteristics as well as uterus of almost normal size can develop. Assisted reproduction techniques (ART), predominantly with donated oocytes, could give these patients the possibility to have children.