ChemInform Abstract: Synthesis of Chiral α‐Trifluoromethylamines with 2, 2, 2‐Trifluoroethylamine as a "Building Block". Issue 29 (29th June 2016)

• Record Type: Journal Article
• Authors: Yan, Wenjin; et al.,
• Is Part Of: ChemInform. Volume 47:Issue 29(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-06-29
• Subjects: indole derivatives, isoindole derivatives -- C‐C bond formation -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism); Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201629138
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The title amines are efficiently prepared by asymmetric SN 2′‐SN 2′ reaction between trifluoroethylisatin ketimines and MBH type carbonates using β‐isocupreidine, a cinchonine derived alkaloid, as catalyst.