The new steroidal glycosides from the aerial parts of Lepidogrammitis drymoglossoides. Issue 9 (1st September 2016)

• Record Type: Journal Article
• Authors: Wei, Hua; Jiang, Hai; Liu, Zhu-Xiang; Li, Gui; Long, Hua; He, Jian-Wu; Chen, Gong-Xi; Yang, Jun-Shan; Ma, Guo-Xu
• Is Part Of: Journal of Asian natural products research. Volume 18:Issue 9(2016)
• Page Start: 878
• Page End: 884
• Publication Date: 2016-09-01
• Subjects: Polypodiaceae -- Lepidogrammitis drymoglossoides -- steroidal glycosides -- cytotoic activity; Materia medica -- Asia -- Periodicals; Pharmacognosy -- Asia -- Periodicals; Medicinal plants -- Asia -- Periodicals; Medicine, Oriental -- Asia -- Periodicals; 615.321095
• DOI: 10.1080/10286020.2016.1171757
• Languages: English
• ISSNs: 1028-6020

Abstract

Abstract: Two new steroidal glycosides ponasteroside C (1 ) and ponasteroside D (2 ) were isolated from the aerial parts of Lepidogrammitis drymoglossoides . Their structures were elucidated by various spectroscopic techniques (IR, HRESIMS, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity against HeLa and HCT-8 cell lines, and compounds1 and2 showed mild activity against all the test cell lines.