Cell immobilization for microbial production of 1, 3-propanediol. (3rd May 2016)

• Record Type: Journal Article
• Authors: Gungormusler-Yilmaz, Mine; Cicek, Nazim; Levin, David B.; Azbar, Nuri
• Is Part Of: Critical reviews in biotechnology. Volume 36:Number 3(2016)
• Page Start: 482
• Page End: 494
• Publication Date: 2016-05-03
• Subjects: Attachment -- biodiesel -- biotechnology -- entrapment -- fermentation -- glycerol; Biotechnology -- Periodicals; Biotechnology -- Periodicals; Review Literature -- Periodicals; Public Health -- Periodicals; Environment -- Periodicals; Industry -- Periodicals; Biotechnology; Review Literature; Public Health; Environment; Industry; 660.6
• DOI: 10.3109/07388551.2014.992386
• Languages: English
• ISSNs: 0738-8551

Abstract

Abstract: Cell and enzyme immobilization are often used for industrial production of high-value products. In recent years, immobilization techniques have been applied to the production of value-added chemicals such as 1, 3-Propanediol (1, 3-PDO). Biotechnological fermentation is an attractive alternative to current 1, 3-PDO production methods, which are primarily thermochemical processes, as it generates high volumetric yields of 1, 3-PDO, is a much less energy intensive process, and generates lower amounts of environmental organic pollutants. Although several approaches including: batch, fed-batch, continuous-feed and two-step continuous-feed were tested in suspended systems, it has been well demonstrated that cell immobilization techniques can significantly enhance 1, 3-PDO production and allow robust continuous production in smaller bioreactors. This review covers various immobilization methods and their application for 1, 3-PDO production.