Lymph nodes can accurately be measured on PET-CT for lymphoma staging/restaging without a concomitant contrast enhanced CT scan. Issue 5 (3rd May 2016)

• Record Type: Journal Article
• Authors: Simpson, William L.; Lee, Karen M.; Sosa, Ninoska; Cooper, Nancy; Scigliano, Eileen; Brody, Joshua D.; Doucette, John T.; Kostakoglu, Lale
• Is Part Of: Leukemia & lymphoma. Volume 57:Issue 5(2016:May)
• Page Start: 1083
• Page End: 1093
• Publication Date: 2016-05-03
• Subjects: Computed tomography -- FDG-avid -- lymph node -- lymphoma -- positron emission tomography; Leukemia -- Periodicals; Lymphomas -- Periodicals; 616.99419
• DOI: 10.3109/10428194.2015.1089437
• Languages: English
• ISSNs: 1042-8194

Abstract

Abstract: Dual imaging with both contrast enhanced CT scan and PET-CT is recommended for evaluation of lymphoma. We compared the performance in identification and size measurements of involved lymph nodes in FDG-avid lymphomas on the low dose non-contrast enhanced CT of a PET-CT scan with those on a diagnostic contrast enhanced CT scan. The size of FDG-avid lymph nodes was measured in both the short and long axis on both the low dose non-contrast CT of the PET-CT and the contrast enhanced CT by two independent readers. A total of 307 FGD avid lymph nodes were identified in 52 patients. There was no statistically significant differences in the measured size of the nodes on the non-contrast and contrast enhanced scans ( p = 0.21). Baseline staging and restaging of FDG-avid lymphomas can be performed with one test, PET-CT, without an accompanying contrast enhanced CT scan, with no effect on the measured nodal size.