Fat grafting for breast cancer patients: From basic science to clinical studies. Issue 8 (August 2016)

• Record Type: Journal Article
• Authors: Gennari, R.; Griguolo, G.; Dieci, M.V.; Guarneri, V.; Tavaniello, B.; Sibilio, A.; Conte, P.
• Is Part Of: European journal of surgical oncology. Volume 42:Issue 8(2016:Aug.)
• Page Start: 1088
• Page End: 1102
• Publication Date: 2016-08
• Subjects: Breast cancer -- Fat grafting -- Lipoffiling -- Oncological outcome -- Safety -- ASCs (adipose stem cells); Oncology -- Periodicals; Cancer -- Surgery -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- surgery -- Periodicals; Cancer -- Chirurgie -- Périodiques; Cancérologie -- Périodiques; Oncologie; Chirurgie (geneeskunde); Electronic journals; Electronic journals -- Sciences; Electronic journals -- Medicine; Electronic journals; 616.994059005
• DOI: 10.1016/j.ejso.2016.04.062
• Languages: English
• ISSNs: 0748-7983

Abstract

Abstract: Fat grafting in the surgical treatment of breast cancer has become popular in a short period of time because of the rising expectations of good esthetic results by the patients as well as the simplicity of the technique; however, the oncological safety for breast cancer patients remains a matter of debate. The procedure raises many questions considering that recent in-vitro studies have shown that fat grafting could promote tumor recurrence through diverse mechanisms, or even facilitate distant metastasis. We present a review of the currently available experimental and clinical data in order to describe and discuss patient selection criteria following breast cancer surgery.