Evaluation of cochlear nerve diameter and cross-sectional area in ANSD patients by 3.0-Tesla MRI. (2nd August 2016)

• Record Type: Journal Article
• Authors: Peng, Liyan; Xiao, Yunfei; Liu, Lei; Mao, Zhongyao; Chen, Qingguo; Zhou, Liangqiang; Liao, Bo; Liu, Aiguo; Wang, Xinglong
• Is Part Of: Acta oto-laryngologica. Volume 136:Number 8(2016)
• Page Start: 792
• Page End: 799
• Publication Date: 2016-08-02
• Subjects: ANSD -- cochlear nerve -- magnetic resonance imaging; Otolaryngology -- Periodicals; Ear -- Diseases -- Periodicals; Throat -- Diseases -- Periodicals; Otolaryngology -- Electronic Resources; Otorhinolaryngologic Diseases; 617.8
• DOI: 10.3109/00016489.2016.1159329
• Languages: English
• ISSNs: 0001-6489

Abstract

Abstract: Conclusions : The size of cochlear nerve (CN) is atrophic in adult auditory neuropathy spectrum disorder (ANSD) patients compared with non-ANSD sensorineural hearing loss (SNHL) patients and normal hearing subjects, and CN deficiency is one of the lesions for ANSD patients.Objectives : To evaluate the dimensions of CN in adult ANSD patients on magnetic resonance imaging (MRI) and confirm the hypothesis that CN deficiency is one of the lesions for ANSD patients.Methods : Medical records and MRI of 24 adult ANSD patients reviewed retrospectively and 20 non-ANSD SNHL and 24 volunteers with normal hearing were recruited as control groups. The long diameter (LD), short diameter (SD), and cross-sectional area (CSA) of CN and facial nerve (FN) were measured.Results : Among the 24 ANSD patients, this study was able to reconstruct and measure the CN of 91.7% (22/24, total 43 ears) of patients and FN of 83.3% (20/24, total 38 ears) of patients. The mean values and standard deviations of LD, SD, and CSA of CN in ANSD patients were 0.65 ± 0.20 mm, 0.44 ± 0.15 mm, and 0.30 ± 0.19 mm 2, respectively. They were significantly smaller in ANSD patients than in control groups ( p < 0.001).