Safe and Selective Nitro Group Reductions Catalyzed by Sustainable and Recyclable Fe/ppm Pd Nanoparticles in Water at Room Temperature. Issue 31 (15th June 2016)

• Record Type: Journal Article
• Authors: Feng, Jie; Handa, Sachin; Gallou, Fabrice; Lipshutz, Bruce H.
• Is Part Of: Angewandte Chemie international edition. Volume 55:Issue 31(2016)
• Page Start: 8979
• Page End: 8983
• Publication Date: 2016-06-15
• Subjects: green chemistry -- micelles -- nanoparticles -- reduction -- water chemistry; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201604026
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: As a result of a unique synergy between ligand‐free Fe/ppm Pd nanoparticles and PEG‐containing designer surfactants, a facile and selective reduction of nitro‐containing aromatics and heteroaromatics can be effected in water at room temperature in the presence of NaBH4 . This new nanotechnology involves low catalyst loadings, is highly chemoselective, and tolerates a wide variety of functional groups. The process, which includes recycling of the entire aqueous medium, offers a general, environmentally responsible, and notably safe approach to highly valued reductions of nitro‐containing compounds. Abstract : By design : As a result of a unique synergy between ligand‐free Fe/ppm Pd nanoparticles and PEG‐containing designer surfactants, a facile and selective reduction of nitro‐containing (hetero)aromatics by NaBH4 can be effected in water at room temperature. The process offers a general, environmentally responsible, and notably safe approach to highly valued reductions of nitro‐containing compounds.