ChemInform Abstract: Expanding the Scope of Primary Amine Catalysis: Stereoselective Synthesis of Indanedione‐Fused 2, 6‐Disubstituted trans‐Spirocyclohexanones. Issue 31 (14th July 2016)

• Record Type: Journal Article
• Authors: Madhusudhan Reddy, G.; Ko, Chi‐Ting; Hsieh, Kai‐Hong; Lee, Chia‐Jui; Das, Utpal; Lin, Wenwei
• Is Part Of: ChemInform. Volume 47:Issue 31(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-07-14
• Subjects: spirocyclic compounds (isocyclic compounds) -- ring closure reactions, annulation reactions -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) -- organocatalysis; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201631076
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: Mechanistic investigation of these organo‐catalytic spirocyclizations reveals two competing pathways: a concerted Diels—Alder reaction and a stepwise Michael addition.