MQAPsingle: A quasi single‐model approach for estimation of the quality of individual protein structure models. Issue 8 (24th May 2016)

• Record Type: Journal Article
• Authors: Pawlowski, Marcin; Kozlowski, Lukasz; Kloczkowski, Andrzej
• Is Part Of: Proteins. Volume 84:Issue 8(2016)
• Page Start: 1021
• Page End: 1028
• Publication Date: 2016-05-24
• Subjects: model quality assessment -- protein structure -- protein prediction -- MQAP -- single‐model MQAP -- model correctness -- CASP10; Proteins -- Periodicals; Proteins -- Periodicals; 572.6
• DOI: 10.1002/prot.24787
• Languages: English
• ISSNs: 0887-3585

Abstract

ABSTRACT: We present a Model Quality Assessment Program (MQAP), called MQAPsingle, for ranking and assessing the absolute global quality of single protein models. MQAPsingle is quasi single‐model MQAP, a method that combines advantages of both "pure" single‐model MQAPs and clustering MQAPs. This approach results in higher accuracy compared to the state‐of‐the‐art single‐model MQAPs. Notably, the prediction for a given model is the same regardless if this model is submitted to our server alone or together with other models. Proteins 2016; 84:1021–1028. © 2015 Wiley Periodicals, Inc.