68Ga-DOTATATE Breast Uptake and Expression in Breast Milk. (August 2016)

• Record Type: Journal Article
• Authors: Forwood, Nicholas J.; Kanthan, Gowri L.; Bailey, Dale L.; Chan, David L.; Schembri, Geoffrey P.
• Is Part Of: Clinical nuclear medicine. Volume 41:Number 8(2016)
• Publication Date: 2016-08
• Subjects: 68Ga-DOTATATE PET/CT -- neuroendocrine tumor -- breastfeeding; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001266
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: The excretion of 68 Ga-DOTA-Octreotate (DOTATATE) and related somatostatin analogues in breast milk has not been demonstrated. We report a case of a 34-year-old woman, 7 months postpartum and breastfeeding, who was referred for DOTATATE imaging after the diagnosis of appendiceal carcinoid and subsequent appendectomy. Prominent breast uptake was noted. A breast milk sample from the patient at 90 minutes postinjection was assayed in a gamma counter and shown to have a concentration of 5.6 Bq/g per MBq administered. The excretion of DOTATATE in breast milk is important to consider when providing radiation safety advice to breastfeeding patients.