Reduction-controlled substrate release from a polymer nanosphere based on a viologen-cavitand. Issue 74 (22nd July 2016)

• Record Type: Journal Article
• Authors: Sultanova, Elza D.; Atlanderova, Anna A.; Mukhitova, Rezeda D.; Salnikov, Vadim V.; Osin, Yuriy N.; Ziganshina, Albina Y.; Konovalov, Alexander I.
• Is Part Of: RSC advances. Volume 6:Issue 74(2016)
• Page Start: 70072
• Page End: 70076
• Publication Date: 2016-07-22
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra15165e
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : In this article, we present a new polymeric nanosphere (p(MVCA- co -SS)) for redox-controlled substrate release. Abstract : In this article, we present a new polymeric nanosphere (p(MVCA- co -SS)) for redox-controlled substrate release. The nanosphere consists of a hydrophobic core with disulfide bridges stabilized by the viologen-resorcinarene cavitand shell. The nanosphere is sensitive to thiol-containing reducing agents: glutathione (GSH) and dithiothreitol (DTT). GSH destructs the hydrophobic core of p(MVCA- co -SS) while DTT integrates into the core increasing its size. The nanosphere as shown can be used as nanocarriers for the redox-controlled substrate release for the fluorescent dyes (pyrene, rhodamine b and fluorescein).