ChemInform Abstract: Iridium‐Catalyzed Asymmetric [3 + 2] Annulation of Aromatic Ketimines with Alkynes via C—H Activation: Unexpected Inversion of the Enantioselectivity Induced by Protic Acids. Issue 34 (4th August 2016)

• Record Type: Journal Article
• Authors: Nagamoto, Midori; Yamauchi, Daisuke; Nishimura, Takahiro
• Is Part Of: ChemInform. Volume 47:Issue 34(2016)
• Page Start: no
• Page End: no
• Publication Date: 2016-08-04
• Subjects: spirocyclic compounds (heterocyclic compounds) -- indan derivatives -- indole derivatives, isoindole derivatives -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) -- ring closure reactions, annulation reactions; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201634101
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: A cationic iridium/binap catalyst enables the asymmetric [3 + 2] annulation of cyclic N‐acyl ketimines with internal alkynes via C—H activation to give spiroaminoindene derivatives with high enantioselectivity.