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ChemInform Abstract: Base‐Catalyzed Asymmetric α‐Functionalization of 2‐(Cyanomethyl)azaarene N‐Oxides Leading to Quaternary Stereocenters. Issue 34 (4th August 2016)
Record Type:
Journal Article
Title:
ChemInform Abstract: Base‐Catalyzed Asymmetric α‐Functionalization of 2‐(Cyanomethyl)azaarene N‐Oxides Leading to Quaternary Stereocenters. Issue 34 (4th August 2016)
Main Title:
ChemInform Abstract: Base‐Catalyzed Asymmetric α‐Functionalization of 2‐(Cyanomethyl)azaarene N‐Oxides Leading to Quaternary Stereocenters.
Abstract: A highly enantioselective α‐functionalization of 2‐(cyanomethyl)pyridine N‐oxides and pyrazine N‐oxides via conjugate addition of 4‐hydroxy‐4‐methylpent‐1‐en‐3‐one or α‐amination with di(tert‐butyl) or dibenzyl azodicarboxylate is developed.