Synthesis of functionalized N-doped graphene DNA hybrid material in a deep eutectic solvent. Issue 15 (20th May 2016)

• Record Type: Journal Article
• Authors: Bhatt, Jitkumar; Mondal, Dibyendu; Devkar, Ranjitsinh V.; Prasad, Kamalesh
• Is Part Of: Green chemistry. Volume 18:Issue 15(2016)
• Page Start: 4297
• Page End: 4302
• Publication Date: 2016-05-20
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c6gc00853d
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : A functionalized DNA and N-doped graphene based non-toxic hybrid material is prepared using a deep eutectic solvent. Abstract : Herewith we have utilized the ability of a choline based deep eutectic solvent (DES) to dissolve DNA and disperse graphene for the synthesis of a Fe3 O4 functionalized DNA–N-doped graphene hybrid material. N-Doped graphene prepared from graphene oxide and melamine by solar radiation was found to envelop the Fe3 O4 functionalized DNA in a sandwich fashion. Attachment of Fe3 O4 nanoparticles and N-doped graphene on the DNA structure and long term preservation of the conformation of DNA in the hybrid material was established. The magnetic hybrid material thus generated does not appear to inhibit the growth of mammalian cells in vitro and thus demonstrates their non-toxic nature, which is useful for biomedical applications.