Tris-ureas as transmembrane anion transporters. Issue 29 (6th July 2016)

• Record Type: Journal Article
• Authors: Olivari, Martina; Montis, Riccardo; Berry, Stuart N.; Karagiannidis, Louise E.; Coles, Simon J.; Horton, Peter N.; Mapp, Lucy K.; Gale, Philip A.; Caltagirone, Claudia
• Is Part Of: Dalton transactions. Volume 45:Issue 29(2016)
• Page Start: 11892
• Page End: 11897
• Publication Date: 2016-07-06
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c6dt02046a
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : Tris ureas can mediate the exchange of Cl − /NO3 − and also Cl − /HCO3 − across bilayer membranes. Abstract : Nine tris-urea receptors (L 1 –L 9 ) have been synthesised and shown to coordinate to a range of anionic guests both by 1 H NMR titration techniques and single crystal X-ray structural analysis. The compounds have been shown to be capable of mediating the exchange of chloride and nitrate and also chloride and bicarbonate across POPC or POPC : cholesterol 7 : 3 vesicle bilayer membranes at low transporter loadings. An interesting dependency of anion transport on the nature of the cation is evidence to suggest that a M + /Cl − cotransport process may also contribute to the release of chloride from the vesicles.