Non-directed aromatic C–H amination: catalytic and mechanistic studies enabled by Pd catalyst and reagent design. Issue 14 (5th April 2016)

• Record Type: Journal Article
• Authors: Bandara, H. M. D.; Jin, D.; Mantell, M. A.; Field, K. D.; Wang, A.; Narayanan, R. P.; Deskins, N. A.; Emmert, M. H.
• Is Part Of: Catalysis science & technology. Volume 6:Issue 14(2016)
• Page Start: 5304
• Page End: 5310
• Publication Date: 2016-04-05
• Subjects: Catalysis -- Periodicals; 541.395
• DOI: 10.1039/c6cy00457a
• Languages: English
• ISSNs: 2044-4753

Abstract

Abstract : The systematic development of pyridine-type ligands and electrophilic amination reagents is described, which promote aromatic Pd catalyzed, non-directed C–H aminations. Abstract : This manuscript describes the systematic development of pyridine-type ligands, which promote the Pd catalyzed, non-directed amination of benzene in combination with novel, hydroxylamine-based electrophilic amination reagents. DFT calculations and mechanistic experiments provide insights into the factors influencing the arene C–H amination protocol.