Clinical neurocardiology defining the value of neuroscience‐based cardiovascular therapeutics. (14th June 2016)

• Record Type: Journal Article
• Authors: Shivkumar, Kalyanam; Ajijola, Olujimi A.; Anand, Inder; Armour, J. Andrew; Chen, Peng‐Sheng; Esler, Murray; De Ferrari, Gaetano M.; Fishbein, Michael C.; Goldberger, Jeffrey J.; Harper, Ronald M.; Joyner, Michael J.; Khalsa, Sahib S.; Kumar, Rajesh; Lane, Richard; Mahajan, Aman; Po, Sunny; Schwartz, Peter J.; Somers, Virend K.; Valderrabano, Miguel; Vaseghi, Marmar; Zipes, Douglas P.
• Is Part Of: Journal of physiology. Volume 594:Number 14(2016:Jul.)
• Page Start: 3911
• Page End: 3954
• Publication Date: 2016-06-14
• Subjects: Physiology -- Periodicals; 612.005
• DOI: 10.1113/JP271870
• Languages: English
• ISSNs: 0022-3751

Abstract

Abstract : Abstract: The autonomic nervous system regulates all aspects of normal cardiac function, and is recognized to play a critical role in the pathophysiology of many cardiovascular diseases. As such, the value of neuroscience‐based cardiovascular therapeutics is increasingly evident. This White Paper reviews the current state of understanding of human cardiac neuroanatomy, neurophysiology, pathophysiology in specific disease conditions, autonomic testing, risk stratification, and neuromodulatory strategies to mitigate the progression of cardiovascular diseases.