Recruitment and Deoxygenation of Selected Respiratory and Skeletal Muscles During Incremental Loading in Stable COPD Patients. Issue 4 (July 2016)

• Record Type: Journal Article
• Authors: Reid, W. Darlene; Sheel, A. William; Shadgan, Babak; Garland, S. Jayne; Road, Jeremy D.
• Is Part Of: Journal of cardiopulmonary rehabilitation and prevention. Volume 36:Issue 4(2016)
• Publication Date: 2016-07
• Subjects: chronic obstructive pulmonary disease -- near-infrared spectroscopy -- respiratory muscles -- skeletal muscles; Cardiopulmonary system -- Diseases -- Patients -- Rehabilitation -- Periodicals; Cardiopulmonary system -- Diseases -- Prevention -- Periodicals; 616.103
• DOI: 10.1097/HCR.0000000000000185
• Languages: English
• ISSNs: 1932-7501

Abstract

Abstract : PURPOSE: To evaluate changes in oxygenated (O2 Hb), deoxygenated (HHb), and total hemoglobin (tHb) of the sternocleidomastoid (SCM), parasternal (PS), biceps (BC), and tibialis anterior (TA) using near-infrared spectroscopy during incremental loading of the inspiratory muscles and the elbow flexors in people with stable chronic obstructive pulmonary disease. METHODS: Fifteen participants with obstructive pulmonary disease were recruited in a repeated-measures crossover design. Near-infrared spectroscopy optodes were applied over the SCM, PS, BC, and TA to measure O2 Hb, HHb, and tHb. Participants were randomly assigned to perform incremental inspiratory threshold loading or elbow flexor loading that imposed higher loads every 2 minutes until task failure. At least 1 week later, participants performed the other test. Arterial oxygen saturation (SpO2 ) was monitored continuously. RESULTS: O2 Hb of the main agonist muscles, SCM and BC, decreased compared with the other muscles during inspiratory threshold loading and elbow flexor loading, respectively. SCM O2 Hb and BC O2 Hb decreased at higher loads compared with baseline. SCM tHb and HHb increased, whereas TA tHb decreased during inspiratory threshold loading. tHb did not change among any muscles during elbow flexor loading. SpO2 did not change from baseline to task failure. CONCLUSIONS: Our data suggest that the SCM was recruited progressively during incremental inspiratory threshold loading; however, O2 Hb was not maintained in this muscle. Similarly, O2 Hb was not maintained in the biceps during elbow flexor loading. This regional deoxygenation in SCM and BC during incremental loading protocols was not reflected by a decrease in SpO2 . Abstract : Near-infrared spectroscopy evaluated regional muscle oxygenation of the inspiratory and arm muscles during incremental loading protocols. Oxygenated hemoglobin levels decreased significantly in the sternocleidomastoid and biceps during the respective incremental loading protocols. Near-infrared spectroscopy identified regional deoxygenation in exercising muscle that was not detected by pulse oximetry.