Rhodium(iii)-catalyzed alkylation of primary C(sp3)–H bonds with α-diazocarbonyl compounds. Issue 62 (12th July 2016)

• Record Type: Journal Article
• Authors: Hou, Wei; Yang, Yaxi; Wu, Yunxiang; Feng, Huijin; Li, Yuanchao; Zhou, Bing
• Is Part Of: Chemical communications. Volume 52:Issue 62(2016)
• Page Start: 9672
• Page End: 9675
• Publication Date: 2016-07-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c6cc03846h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Rh(iii )-catalyzed intermolecular chelation-assisted insertion of primary sp 3 C–H bonds into α-diazocarbonyl compounds, for the first time, is reported under mild reaction conditions. Abstract : Rh(iii )-catalyzed intermolecular chelation-assisted insertion of carbenes derived from α-diazocarbonyl compounds into non-acidic primary sp 3 C–H bonds, for the first time, is reported under mild reaction conditions, thus affording a good complement to previous metal-carbenoid-induced primary C(sp 3 )–H insertion reactions. We believe that this method will open up a new avenue for primary sp 3 C–H functionalization with α-diazocarbonyl compounds.