The Dilemma of Breast Cancer Treatment and Existing Collagen Vascular Disease: A Case of Scleroderma and Review of the Literature. Issue 4 (28th April 2016)

• Record Type: Journal Article
• Authors: Zaremba, Nicole M.; Tamkus, Deimante; DiCarlo, Luciano; Herman, James; Martin, Mersadies; Bumpers, Harvey L.
• Is Part Of: Breast journal. Volume 22:Issue 4(2016:Jul./Aug.)
• Page Start: 451
• Page End: 455
• Publication Date: 2016-04-28
• Subjects: breast cancer -- collagen vascular disease -- radiation therapy -- scleroderma; Breast -- Diseases -- Periodicals; Breast -- Cancer -- Periodicals; 618.19
• DOI: 10.1111/tbj.12600
• Languages: English
• ISSNs: 1075-122X

Abstract

Abstract: Collagen vascular diseases present a treatment dilemma for patients with breast cancer. Due to the potential for severe, acute, and late complications of radiation therapy, a history of collagen vascular disease (CVD) is a relative contraindication to breast‐conserving treatment. We present a case of early stage breast cancer in a patient with severe scleroderma treated with breast‐conserving surgery without radiation and a brief review of the published literature regarding the therapeutic approach to the patient with CVD and breast cancer.