Serum lipid levels were related to socio‐demographic characteristics in a German population‐based child cohort. (22nd May 2016)

• Record Type: Journal Article
• Authors: Dathan‐Stumpf, Anne; Vogel, Mandy; Rieger, Kristin; Thiery, Joachim; Hiemisch, Andreas; Kiess, Wieland
• Is Part Of: Acta pædiatrica. Volume 105:Number 8(2016)
• Page Start: e360
• Page End: e367
• Publication Date: 2016-05-22
• Subjects: Family Affluence Scale -- LIFE Child study -- Serum lipids -- Socio‐demographics -- Winkler index; Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.13438
• Languages: English
• ISSNs: 0803-5253

Abstract

Abstract: Aim: Socio‐demographic factors affect the development and lives of children and adolescents. We examined links between serum lipids and apolipoproteins and socio‐demographic factors in the Leipzig Research Centre for Civilization Diseases Child (LIFE Child) study. Methods: The Winkler index and the Family Affluence Scale were used to define characteristics of the social status of 938 boys and 860 girls aged from birth to 19 years. We then used univariate and multivariate regression analyses to examine the socio‐demographic impact on total cholesterol, low‐density lipoprotein (LDL) cholesterol, high‐density lipoprotein (HDL), cholesterol triglycerides and apolipoproteins A1 (ApoA1) and B (ApoB). Results: No significant influences on the Winkler index or the Family Affluence Scale were observed regarding the concentrations of serum lipids for total cholesterol or LDL cholesterol. However, and most importantly, children and adolescents with high social status and high family affluence showed significantly higher HDL cholesterol and ApoA1 levels than those with lower individual totals. A higher Winkler index was associated with significantly lower values for triglycerides and ApoB. Conclusion: Adolescents with higher family wealth and social status showed a lower cardiovascular risk profile, as measured by the concentrations of HDL cholesterol and triglycerides as well as ApoA1 and B.