Carbon Paste Electrodes Modified with Graphene Oxides – Comparative Electrochemical Studies of Thioguanine. Issue 7 (22nd February 2016)

• Record Type: Journal Article
• Authors: Smarzewska, Sylwia; Pokora, Joanna; Leniart, Andrzej; Festinger, Natalia; Ciesielski, Witold
• Is Part Of: Electroanalysis. Volume 28:Issue 7(2016)
• Page Start: 1562
• Page End: 1569
• Publication Date: 2016-02-22
• Subjects: thioguanine -- drug analysis -- graphene oxide -- reduced graphene oxide -- square wave stripping voltammetry; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201501101
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: The voltammetric study of thioguanine (TG) was comparatively investigated on bare, graphene oxide and reduced graphene oxide modified carbon paste electrodes using cyclic (CV) and square wave stripping (SWSV) voltammetric techniques. Depending on the working electrode and pH of supporting electrolyte, characteristic electrochemical behaviour of thioguanine was established and the mechanism of TG oxidation was suggested. Based on the obtained results, the new voltammetric method for TG determination in buffer solutions and pharmaceutical formulation was developed. Atomic force microscopy was used to characterize electrodes surfaces. Abstract :