Inside Back Cover: A Major Advance in the Synthesis of Fluoroalkyl Pyrazoles: Tuneable Regioselectivity and Broad Substitution Patterns (Chem. Eur. J. 32/2016). Issue 32 (20th June 2016)

• Record Type: Journal Article
• Authors: Schmitt, Etienne; Panossian, Armen; Vors, Jean‐Pierre; Funke, Christian; Lui, Norbert; Pazenok, Sergiy; Leroux, Frédéric R.
• Is Part Of: Chemistry. Volume 22:Issue 32(2016)
• Page Start: 11471
• Page End: 11471
• Publication Date: 2016-06-20
• Subjects: cyclization -- fluoroalkyl amino reagents -- nitrogen heterocycles -- regioselectivity -- synthetic methods; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201602703
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : Fluoroalkyl pyrazoles, which are key building blocks in agrochemistry and promising candidates in life‐science‐oriented research, have shown much potential in accessing a variety of bis(fluoroalkyl)pyrazoles with tunable regioselectivity of the hydrazine addition, via two intermediates of opposed reactivity. The two strategies are represented by one slingshot aiming at two different targets, with a background of crops, forests, and laboratory activities. More information can be found in the Full Paper by S. Pazenok, F. R. Leroux et al. on page11239 .