Size‐Controlled Formation of Noble‐Metal Nanoparticles in Aqueous Solution with a Thiol‐Free Tripeptide. (21st April 2016)

• Record Type: Journal Article
• Authors: Corra, Stefano; Lewandowska, Urszula; Benetti, Edmondo M.; Wennemers, Helma
• Is Part Of: Angewandte Chemie. Volume 128:Number 30(2016)
• Page Start: 8684
• Page End: 8687
• Publication Date: 2016-04-21
• Subjects: Edelmetalle -- Kombinatorische Chemie -- Nanopartikel -- Peptide -- Selbstorganisierte Monoschichten; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201510337
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: A combinatorial screening revealed the peptide H‐His‐d ‐Leu‐d ‐Asp‐NH2 (1 ) as an additive for the generation of monodisperse, water‐soluble palladium nanoparticles with average diameters of 3 nm and stabilities of over 9 months. The tripeptide proved to be also applicable for the size‐controlled formation of other noble‐metal nanoparticles (Pt and Au). Studies with close analogues of peptide1 revealed a specific role of each of the three amino acids for the formation and stabilization of the nanoparticles. These data combined with microscopic and spectroscopic analyses provided insight into the structure of the self‐assembled peptidic monolayer around the metal core. The results open interesting prospects for the development of functionalized metal nanoparticles.