A Mitochondrion‐Specific Photoactivatable Fluorescence Turn‐On AIE‐Based Bioprobe for Localization Super‐Resolution Microscope. Issue 25 (2nd May 2016)

• Record Type: Journal Article
• Authors: Gu, Xinggui; Zhao, Engui; Zhao, Teng; Kang, Miaomiao; Gui, Chen; Lam, Jacky W. Y.; Du, Shengwang; Loy, Michael M. T.; Tang, Ben Zhong
• Is Part Of: Advanced materials. Volume 28:Issue 25(2016)
• Page Start: 5064
• Page End: 5071
• Publication Date: 2016-05-02
• Subjects: fluorescence turn‐on -- mitochondrion‐specific -- photoactivatable fluorophores -- photocyclodehydrogenation -- super‐resolution imaging; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201505906
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : A novel mitochondrion‐specific photo­activatable fluorescence turn‐on bioprobe, named as o ‐TPE‐ON+, is designed and readily prepared, operating through a new photoactivatable mechanism of photocyclodehydrogenation. This bioprobe exhibits unique photoactivation behavior in cells, and is applied to super‐resolution imaging of mitochondrion and its dynamic investigation in both fixed and live cells under physiological conditions without any external additives.