Linking up at the BAR: Oligomerization and F-BAR protein function. Issue 15 (2nd August 2016)

• Record Type: Journal Article
• Authors: McDonald, Nathan A.; Gould, Kathleen L.
• Is Part Of: Cell cycle. Volume 15:Issue 15(2016)
• Page Start: 1977
• Page End: 1985
• Publication Date: 2016-08-02
• Subjects: actin cytoskeleton -- cell motility -- cytokinesis -- endocytosis -- F-BAR domain -- membrane bending -- membrane binding -- oligomerization -- scaffolding -- signaling -- tubulation; Cell cycle -- Periodicals; 571.84377
• DOI: 10.1080/15384101.2016.1190893
• Languages: English
• ISSNs: 1538-4101

Abstract

ABSTRACT: As cells grow, move, and divide, they must reorganize and rearrange their membranes and cytoskeleton. The F-BAR protein family links cellular membranes with actin cytoskeletal rearrangements in processes including endocytosis, cytokinesis, and cell motility. Here we review emerging information on mechanisms of F-BAR domain oligomerization and membrane binding, and how these activities are coordinated with additional domains to accomplish scaffolding and signaling functions.