Congenital malformations and other reproductive losses in goats due to poisoning by Poincianella pyramidalis (Tul.) L.P. Queiroz (=Caesalpinia pyramidalis Tul.). (August 2016)

• Record Type: Journal Article
• Authors: Santos dos Reis, Suélen Dias; de Oliveira, Ricardo Santana; Correia Marcelino, Sóstenes Apolo; Silva Almeida e Macêdo, Juliana Targino; Riet-Correa, Franklin; da Anunciação Pimentel, Luciano; Ocampos Pedroso, Pedro Miguel
• Is Part Of: Toxicon. Volume 118(2016)
• Page Start: 91
• Page End: 94
• Publication Date: 2016-08
• Subjects: Abortion -- Embryonic death -- Malformations -- Small ruminants -- Toxic plants; Toxins -- Periodicals; Venom -- Periodicals; 615.9
• DOI: 10.1016/j.toxicon.2016.04.043
• Languages: English
• ISSNs: 0041-0101

Abstract

Abstract: In the semiarid region of Brazil, in areas with vegetation composed mainly of Poincianella pyramidalis, several cases of congenital malformation and reproductive losses were observed in goats and sheep from 2012 to 2014. To determine the teratogenic effect of P. pyramidalis, two groups of eight goats each were used. Goats from Group 1 received fresh P. pyramidalis, harvested daily, as the only roughage during the whole breeding and pregnancy period. Goats in Group 2 (control) received Cynodon dactylon (tifton) hay free choice. Ultrasound examination for pregnancy diagnosis was performed every 28 days. Four goats from Group 1 were pregnant on day 28 but not on day 56, suggesting embryonic death or abortion. Another goat from Group 1 died at day 70 of pregnancy, and the fetuses exhibited micrognathia. The other three goats bore six kids, three of which showed bone malformations in the limbs, spine, ribs, sternum, and head, including arthrogryposis, scoliosis and micrognathia. One kid also showed hypoplasia of the left pulmonary lobes. In the control group, all goats bore a total of 13 kids and none of them exhibited malformations. These results demonstrated that P. pyramidalis causes congenital malformations and other reproductive losses in goats. Highlights: Poincianella pyramidalis is a common plant in the Brazilian semiarid region. Malformations in sheep and goats are associated with the ingestion of this plant. To demonstrate this association P. pyramidalis was administrated to pregnant goats. Experimentally P. pyramidalis caused embryonic deaths, abortion and malformations P . pyramidalis is a cause of malformations and reproductive losses in goats and sheep.