Fe3O4-nanoparticles catalyzed an efficient synthesis of nitriles from aldehydes. Issue 32 (10th August 2016)

• Record Type: Journal Article
• Authors: Ghosh, Pranab; Saha, Bittu; Pariyar, Gyan Chandra; Tamang, Abiral; Subba, Raju
• Is Part Of: Tetrahedron letters. Volume 57:Issue 32(2016)
• Page Start: 3618
• Page End: 3621
• Publication Date: 2016-08-10
• Subjects: Aldehydes -- Nitriles -- Fe3O4-CTAB NPs -- DMF -- Reflux; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2016.06.125
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Easy reaction set up. Simple and easy workup procedure. Economically benefited. Abstract: Fe3 O4 -CTAB NPs have been applied as a competent catalyst for one-pot synthesis of nitriles directly from aldehydes. The present investigation describes the synthesis of nitriles by combination of aromatic/aliphatic/heterocyclic aldehydes and hydroxylamine hydrochloride in the presence of iron oxide nanocatalyst in DMF under reflux condition. Fe3 O4 -CTAB NPs were prepared by reported method and characterized by FE-SEM, TEM, and XRD analysis. The amount of Fe in Fe3 O4 -CTAB was quantified by Atomic Absorption Spectroscopy (AAS). The protocol endow with excellent yield of products along with simple reaction set up and economically adept alternative approach.