Minocycline for the treatment of cutaneous silicone granulomas: A case report. (2nd January 2016)

• Record Type: Journal Article
• Authors: Crocco, Elisete; Pascini, Mirella; Suzuki, Nathalie; Alves, Renata; Proença, Thais; Lellis, Rute
• Is Part Of: Journal of cosmetic and laser therapy. Volume 18:Number 1(2016:Feb.)
• Page Start: 48
• Page End: 49
• Publication Date: 2016-01-02
• Subjects: foreign-body granuloma -- minocycline -- silicone oils; Skin -- Laser surgery -- Periodicals; Surgery, Plastic -- Periodicals; 617.477
• DOI: 10.3109/14764172.2015.1052514
• Languages: English
• ISSNs: 1476-4172

Abstract

Abstract : Silicone oil injections are often used for soft tissue augmentation and local and general adverse effects occurring from a few months to 15 years after injection have been reported. Here, we present a case of delayed granuloma formation due to liquid injectable silicone with large extent of involvement, which precluded surgical removal. Our patient was successfully treated with minocycline, considering its anti-inflammatory, immunomodulating and antigranulomatous properties. This case presents minocycline monotherapy as a useful treatment option for the management of severe granuloma induced by silicone use when surgical excision is not possible.