Comparison of serum zinc, calcium, and magnesium concentrations in women with pregnancy-induced hypertension and healthy pregnant women: A meta-analysis. (2nd April 2016)

• Record Type: Journal Article
• Authors: He, Lianping; Lang, Lin; Li, Yijun; Liu, Qingqing; Yao, Yingshui
• Is Part Of: Hypertension in pregnancy. Volume 35:Number 2(2016)
• Page Start: 202
• Page End: 209
• Publication Date: 2016-04-02
• Subjects: Calcium -- case-control study -- hypertension -- magnesium -- zinc; Hypertension in pregnancy -- Periodicals; Pregnancy -- Complications -- Periodicals; 618.3261
• DOI: 10.3109/10641955.2015.1137584
• Languages: English
• ISSNs: 1064-1955

Abstract

ABSTRACT: Objective : The relationship between serum zinc, magnesium, and calcium levels and pregnancy-induced hypertension (PIH) is controversial. The aim of our study was to determine whether or not serum zinc, magnesium, and calcium levels are associated with PIH. Methods : In our study, we searched databases, including Wangfang, Chinese National Knowledge Infrastructure, and PubMed, to find literature regarding the relationship between PIH and serum trace elements. Meta-analysis was performed using the Review Manager5.3 software. Results : A total of 14 articles were included in our study. The results of the meta-analysis indicated that patients with PIH had lower serum zinc (SMD = −1.14; 95% CI] = −1.69, −0.59; P < 0.05), calcium (MD = −0.26; 95% CI = −0.36, −0.15; P < 0.05), and magnesium concentration (MD = −0.0.06; 95% CI = −0.08, −0.05; P < 0.05) than healthy gravidas. Conclusion : Our research suggests that serum zinc, calcium, and magnesium concentrations may have an effect on PIH. Thus, the serum zinc, calcium, and magnesium levels could be measured for PIH patients.