Simultaneous Evaluation of Magnesia and Silica Contents' Effect on in-vitro Bioactivity of Novel Bioglasses in the SiO2-CaO-MgO System. Issue 1 (2nd January 2016)

• Record Type: Journal Article
• Authors: Eslami, Masoud; Mahdieh, Zahra; Maddahi, Vahid; Shokrgozar, Mohammad Ali; Mehrjoo, Morteza
• Is Part Of: Transactions of the Indian Ceramic Society. Volume 75:Issue 1(2016)
• Page Start: 7
• Page End: 11
• Publication Date: 2016-01-02
• Subjects: Bioglass -- Silica -- Bioactivity -- Magnesia; Pottery -- India -- Periodicals; 666.306254
• DOI: 10.1080/0371750X.2015.1131628
• Languages: English
• ISSNs: 0371-750X

Abstract

ABSTRACT: In this study, bioglasses in SiO2 -CaO-MgO system were synthesized through sol-gel method and the effect of silica and magnesia contents on in-vitro bioactivity of the bioglasses were investigated. XRD patterns showed an amorphous structure after heat treatment at 600°C for 2 h for all glasses and also indicated that after immersion in SBF, apatite particles precipitated on glass surfaces and the rate of apatite formation decreased with increasing Mg/Ca ratio. On the other hand, the apatite formation rate was enhanced with increasing the silica content. Furthermore, magnesia contents increased the compressive strength of the samples. According to SEM, higher Mg/Ca ratio led to increase in particle size of the precipitated apatite. MTT assay showed that cell proliferation was inhibited with increasing Mg/Ca ratio, however, silica contents stimulated the osteoblast proliferation. GRAPHICAL ABSTRACT: