Amplified effect of surface charge on cell adhesion by nanostructures. Issue 25 (6th May 2016)

• Record Type: Journal Article
• Authors: Xu, Li-Ping; Meng, Jingxin; Zhang, Shuaitao; Ma, Xinlei; Wang, Shutao
• Is Part Of: Nanoscale. Volume 8:Issue 25(2016)
• Page Start: 12540
• Page End: 12543
• Publication Date: 2016-05-06
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c6nr00649c
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : The effect of surface charge on cell adhesion can be significantly amplified by integrating nanostructures, as revealed by cell adhesion performance, cell morphology and corresponding cytoskeletal organization. Abstract : Nano-biointerfaces with varied surface charge can be readily fabricated by integrating a template-based process with maleimide–thiol coupling chemistry. Significantly, nanostructures are employed for amplifying the effect of surface charge on cell adhesion, as revealed by the cell-adhesion performance, cell morphology and corresponding cytoskeletal organization. This study may provide a promising strategy for developing new biomedical materials with tailored cell adhesion for tissue implantation and regeneration.