Coordination polymer hydrogels through Ag(i)-mediated spontaneous self-assembly of unsubstituted nucleobases and their antimicrobial activity. Issue 67 (30th June 2016)

• Record Type: Journal Article
• Authors: Sharma, Bhagwati; Mahata, Arup; Mandani, Sonam; Sarma, Tridib K.; Pathak, Biswarup
• Is Part Of: RSC advances. Volume 6:Issue 67(2016)
• Page Start: 62968
• Page End: 62973
• Publication Date: 2016-06-30
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra11137h
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : The formation of effective antimicrobial metallogels through Ag(i ) ion mediated self-assembly of unsubstituted nucleobases is reported. The Ag–pyrimidine gels could further reduce Ag + ions to Ag nanoparticles decorated along the nanofibers. Abstract : Spontaneous formation of metallogels through the self-assembly of unsubstituted nucleobases with Ag(i ) ions is reported. Whereas adenine, cytosine, thymine and uracil form metallogels under deprotonated conditions with nanofibrillar morphology, gelation of guanine with Ag(i ) occurs only under acidic conditions through the self-organization of nanoscale metal–organic particles. In situ reduction of Ag salts occurs in Ag–pyrimidine gels to yield Ag nanoparticles decorated on the gel nanofibers. The Ag–nucleobase hydrogels showed excellent antimicrobial properties against both Gram positive as well as Gram negative bacteria.