Chromogenic and fluorogenic multianalyte detection with a tuned receptor: refining selectivity for toxic anions and nerve agents. Issue 64 (21st June 2016)

• Record Type: Journal Article
• Authors: Kumar, Vinod; Rana, Hemlata; Raviraju, G.; Garg, Prabhat; Baghel, Anuradha; Gupta, A. K.
• Is Part Of: RSC advances. Volume 6:Issue 64(2016)
• Page Start: 59648
• Page End: 59656
• Publication Date: 2016-06-21
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra07080a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : In the present study, a chemical probe was finely tuned for the highly selective and sensitive chromogenic and fluorogenic detection of toxic anions and a nerve agent. Abstract : In the present study, a chemical probe was finely tuned for the highly selective and sensitive chromogenic and fluorogenic detection of toxic anions and a nerve agent. Studies on the binding sites, signaling units and spacers led to a receptor molecule, i.e., 2, 7-bis-[3-(4-cyanophenyl)thiourea] fluorene2, which detected multiple analytes such as fluoride, cyanide, and a tabun mimic. The optical responses obtained from all the three analytes were quite distinct from one another. More importantly, we have been successful in demonstrating the highly specific chromo-fluorogenic detection of a tabun mimic over other chemical warfare agents and reactive and non-reactive electrophilic interferents. In an attempt to mimic real-life scenarios, the applicability of our protocol was further extended to demonstrate the presence of a tabun mimic on solid surfaces, in the gas phase and in a spiked soil sample.