New insights into an innovative Auricularia auricular polysaccharide pH-sensitive hydrogel for controlled protein drug delivery. Issue 64 (21st June 2016)

• Record Type: Journal Article
• Authors: Yu, Yibin; Pan, Hao; Wang, Yingying; Xiong, Wei; Zhang, Qiantao; Chen, Kai; Gai, Xiumei; Li, Pingfei; Yang, Xinggang
• Is Part Of: RSC advances. Volume 6:Issue 64(2016)
• Page Start: 59794
• Page End: 59799
• Publication Date: 2016-06-21
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c6ra06463a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : An innovative pH-sensitive Auricularia auricular polysaccharide hydrogel was developed for effective controlled protein delivery for the first time. Abstract : A novel hydrogel based on Auricularia auricular polysaccharide (AAP), was prepared and characterized. AAP hydrogel exhibited a pH-sensitive release of model protein drug (bovine serum albumin, BSA) under simulated gastrointestinal conditions. The results indicate AAP hydrogel has promising potential as an effective vehicle for oral delivery of protein.