An efficient approach to construct benzisothiazol-3(2H)-ones via copper-catalyzed consecutive reaction of 2-halobenzamides and carbon disulfide. Issue 26 (7th June 2016)

• Record Type: Journal Article
• Authors: Li, Ting; Yang, Lei; Ni, Kaidong; Shi, Zhenyu; Li, Fei; Chen, Dongyin
• Is Part Of: Organic & biomolecular chemistry. Volume 14:Issue 26(2016)
• Page Start: 6297
• Page End: 6303
• Publication Date: 2016-06-07
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c6ob00819d
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An efficient copper-catalyzed reaction for the synthesis of benzisothiazol-3(2 H )-ones has been developed, starting from easily available 2-halobenzamides and carbon disulfide. The reaction proceeds via a consecutive process with S–C bond and S–N bond formation. Abstract : An efficient copper-catalyzed reaction for the synthesis of benzisothiazol-3(2 H )-ones has been developed, starting from easily available 2-halobenzamides and carbon disulfide, which gave the corresponding target products in 30–89% yield for 25 examples. The reaction proceeds via a consecutive process with S–C bond and S–N bond formation.