Enantiodivergent Combination of Natural Product Scaffolds Enabled by Catalytic Enantioselective Cycloaddition. (19th May 2016)
- Record Type:
- Journal Article
- Title:
- Enantiodivergent Combination of Natural Product Scaffolds Enabled by Catalytic Enantioselective Cycloaddition. (19th May 2016)
- Main Title:
- Enantiodivergent Combination of Natural Product Scaffolds Enabled by Catalytic Enantioselective Cycloaddition
- Authors:
- Xu, Hao
Golz, Christopher
Strohmann, Carsten
Antonchick, Andrey P.
Waldmann, Herbert - Abstract:
- Abstract: An efficient strategy has been established for the enantiodivergent synthesis of natural product inspired compounds embodying both tropane and pyrrolidine natural product fragments. This strategy includes the enantioselective kinetic resolution of racemic tropanes by means of a copper(I)‐catalyzed [3+2] cycloaddition and allows the preparation of two enantiopure products in a one‐pot reaction in high yield and with high diastereo‐ and enantioselectivity by using one chiral catalyst.
- Is Part Of:
- Angewandte Chemie. Volume 128:Number 27(2016)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 128:Number 27(2016)
- Issue Display:
- Volume 128, Issue 27 (2016)
- Year:
- 2016
- Volume:
- 128
- Issue:
- 27
- Issue Sort Value:
- 2016-0128-0027-0000
- Page Start:
- 7892
- Page End:
- 7896
- Publication Date:
- 2016-05-19
- Subjects:
- Asymmetrische Katalyse -- Cycloadditionen -- Enantiomere -- Kinetische Racematspaltung -- Tropan
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201602084 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 2098.xml