Vitamin D deficiency among subfertile women: case-control study. (2nd April 2016)

• Record Type: Journal Article
• Authors: Al-Jaroudi, Dania; Al-Banyan, Nora; Aljohani, Naji J.; Kaddour, Ouhoud; Al-Tannir, Mohamad
• Is Part Of: Gynecological endocrinology. Volume 32:Number 4(2016:Apr.)
• Page Start: 272
• Page End: 275
• Publication Date: 2016-04-02
• Subjects: Calcium -- infertility -- Middle Eastern -- supplementation -- vitamin D; Endocrine gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.1
• DOI: 10.3109/09513590.2015.1112784
• Languages: English
• ISSNs: 0951-3590

Abstract

Abstract: Objective : The objective of the study is to compare the dietary vitamin D and calcium intake among subfertile women (cases) versus pregnant women (controls) and to determine the vitamin D levels in the subfertile and pregnant women. The study design was an observational case-control study where a total of 181 (83 previously diagnosed subfertile cases from various causes and 98 pregnant controls) women of reproductive age. A validated questionnaire was used where it focused on key indicators evaluating vitamin D-related factors. Blood was withdrawn for the measurement of serum calcium, albumin and phosphate to exclude secondary causes that might affect vitamin D level. Results : The prevalence of vitamin D deficiency was significantly higher in the subfertile group than controls (59.0% versus 40.4%; p < 0.01). Calcium supplements intake was significantly higher in controls than the subfertile group (64.6% versus 10.0%; p value < 0.001). Total dietary vitamin D intake (> 400 IU/day) was significantly higher in the controls than the subfertile group. Conclusion : Vitamin D deficiency is prevalent among subfertile women. Optimization of serum calcium and vitamin D levels is encouraged.