Androgenetic alopecia as an indicator of metabolic syndrome and cardiovascular risk. (3rd May 2016)

• Record Type: Journal Article
• Authors: Ertas, Ragip; Orscelik, Ozcan; Kartal, Demet; Dogan, Ali; Ertas, Sule Ketenci; Aydogdu, Ebru Guler; Ascioglu, Ozcan; Borlu, Murat
• Is Part Of: Blood pressure. Volume 25:Number 3(2016)
• Page Start: 141
• Page End: 148
• Publication Date: 2016-05-03
• Subjects: Androgenetic alopecia -- arterial stiffness -- cardiovascular risk factors -- carotid intima–media thickness -- insulin resistance -- metabolic syndrome; Blood pressure -- Periodicals; Hypertension -- Periodicals; Hypertension -- Periodicals; Blood Pressure -- Periodicals; 612.14
• DOI: 10.3109/08037051.2015.1111021
• Languages: English
• ISSNs: 0803-7051

Abstract

Abstract: Numerous studies have investigated a probable association between androgenetic alopecia (AGA) and cardiovascular disease (CVD) by researching limited and dispersed parameters. We aimed to evaluate both traditional and non-traditional cardiovascular risk factors in male patients with early-onset AGA. This case–control study included 68 participants: 51 male patients with early-onset AGA and 17 healthy male controls. Patients with AGA were classified into three groups according to the Hamilton–Norwood scale and the presence of vertex hair loss. Traditional and non-traditional cardiovascular risk factors were examined in all study subjects. Metabolic syndrome was diagnosed in 25 patients with AGA and in two control subjects ( p < 0.05). The carotid intima–media thickness values were found to be significantly higher in patients with vertex pattern AGA than in patients without vertex baldness and controls ( p < 0.05). The pulse-wave velocity values were also found to be significantly higher in patients ( p < 0.001). A limitation of this study was the small study population. In conclusion, vertex pattern AGA appears to be a marker for early atherosclerosis. This finding supports the hypothesis that early-onset AGA alone could be an independent risk factor for CVD and metabolic syndrome.