Topologically-associating domains: gene warehouses adapted to serve transcriptional regulation. Issue 3 (26th May 2016) - Razin, Sergey V.
ABSTRACT: Structural-functional domains have long been hypothesized to occur in eukaryotic chromosomes, but their existence still remains controversial. Here, we discuss the current state of studies of 3D genome folding and the relation of this folding to the functional organization of the genome.