Pulmonary endarterectomy for the treatment of chronic thromboembolic pulmonary hypertension. (2nd June 2016)

• Record Type: Journal Article
• Authors: Guth, Stefan; Wiedenroth, Christoph B.; Kramm, Thorsten; Mayer, Eckhard
• Is Part Of: Expert review of respiratory medicine. Volume 10:Number 6(2016)
• Page Start: 673
• Page End: 684
• Publication Date: 2016-06-02
• Subjects: Pulmonary endarterectomy -- PEA -- chronic thromboembolic pulmonary hypertension -- CTEPH -- pulmonary hypertension -- pulmonary embolism -- balloon pulmonary angioplasty -- BPA; Respiratory organs -- Diseases -- Periodicals; Respiratory organs -- Diseases -- Treatment -- Periodicals; 616.2005
• DOI: 10.1080/17476348.2016.1176915
• Languages: English
• ISSNs: 1747-6348

Abstract

ABSTRACT: Pulmonary endarterectomy is a curative treatment option for patients with chronic thromboembolic pulmonary hypertension (CTEPH). There is a growing body of evidence suggesting that not only patients with CTEPH but also patients with pulmonary arterial obstructions and mean pulmonary artery pressures < 25 mmHg should be offered surgery. In this review, the recent literature regarding pathophysiology, diagnostic methods, decision making by an expert CTEPH team, and surgical techniques will be summarized. Novel alternative treatment options for inoperable CTEPH patients will be discussed, i.e. targeted medical therapy and balloon pulmonary angioplasty. For the future the major task will be to define a clear selection process for the optimal treatment of the individual CTEPH patient.